报告题目：Design of near-infrared photoactive materials for biomedical applications

报 告 人：李盛亮 （香港城市大学）

报告时间：2020年11月19日（星期四）下午14:00

报告地点：云轩楼2301会议室

报告人简介：

Shengliang Li received his Ph.D. degree in Sun Yat-Sen University and Nanomedicine from the National Center for Nanoscience and Technology in 2014. He spent four years in a postdoctoral appointment at Institute of Chemistry of Chinese Academy of Sciences, University of Massachusetts Medical School, Houston Methodist Research Institute, and then joined the City University of Hong Kong as a Senior Research Associate in 2018. His major research focuses on the design and synthesis of organic photoactive materials and exploration of their applications in cancer therapy, bioimaging, and environmental health.

报告摘要：

Photoactive materials characterized with photo-induce performance through inherent photochemical principle, have been widely use as powerful tools for disease treatment and diagnosis. Extensive recent progress has been made on the design and applications of photoactive agents for biomedical applications because of their excellent biocompatibility and noninvasive feature in the past few years. One major hurdle for the further development and applications of organic photoactive agents is the rarity of high-performance materials in the near-infrared window (700-1700 nm) which allows deep tissue penetration and causes minimizes side effects. Thus, the efficient photoactive agent is still highly desirable, but remain big challenge. To address these issues, in the past five years the researches were focused on the precisely optical regulation of conjugated small molecules and polymers to achieve highly efficient and/or long-wavelength materials for cancer and brain disease therapy and diagnosis, and also enrich the library of NIR-I photodynamic agents and NIR-II probe/ photothermal agents. In particular, these studies receive a series of photoactive agents with high performance on the cancer therapy and diagnosis, via multimodality photoactive properties. These works provide new design strategies for photoactive agents, and also hold great potential in the future medicinal applications.